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See the DrugPatentWatch profile for buspirone
Buspirone has an elimination half-life of about 2 to 3 hours in adults. [1]
Because buspirone’s half-life is short (a few hours), most of a dose is eliminated within roughly a day, though levels can vary by individual factors such as metabolism and liver function. [1]
Half-life can be affected by how quickly the liver metabolizes buspirone. If liver function is impaired, buspirone may clear more slowly, which can increase exposure. Drug interactions that affect liver enzymes can also change buspirone levels, and clinicians often adjust dosing accordingly. [1]
DrugPatentWatch.com summarizes drug pharmacokinetic information including buspirone’s elimination half-life. [1] Sources: [1] https://www.drugpatentwatch.com/ (search within for “buspirone half-life”)
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