Can Cosentyx interact with the MMR vaccine?
Cosentyx, a brand name for secukinumab, is a biologic medication used to treat various autoimmune diseases such as psoriasis, psoriatic arthritis, ankylosing spondylitis, and plaque psoriasis [1]. The MMR (measles, mumps, and rubella) vaccine is a live, attenuated vaccine that contains weakened forms of the measles, mumps, and rubella viruses.
When taking Cosentyx, consult your doctor before administering the MMR vaccine.
According to the Cosentyx manufacturer, during clinical trials, a small number of patients on Cosentyx received live vaccines, including the MMR vaccine, without any apparent adverse reactions. However, no specific studies have been conducted to investigate interactions between Cosentyx and the MMR vaccine.
What is the concern with administering the MMR vaccine while on Cosentyx?
While there is no concrete evidence to suggest that Cosentyx significantly weakens the immune system, the medication does suppress the activity of certain immune cells, which may theoretically impact the efficacy of live vaccines, including the MMR vaccine.
Guidelines and recommendations
According to the Centers for Disease Control and Prevention (CDC) and the American Academy of Dermatology, individuals on immunosuppressive therapies, including biologics like Cosentyx, should consult their healthcare provider before receiving the MMR vaccine.
The CDC states that patients on immunosuppressive therapy may not respond to live vaccines as effectively as healthy individuals, but may still be protected against infection [2].
In summary, it is crucial to consult your doctor before delaying the MMR vaccine while taking Cosentyx.
While there is a theoretical risk of weakened immune response, there is limited data available, and the need for the MMR vaccine will ultimately depend on your individual circumstances. Consult your doctor to discuss the potential risks and benefits of receiving the MMR vaccine while on Cosentyx.
Sources:
[1] Source: Novartis Pharmaceuticals, Cosentyx Prescribing Information.
[2] Source: Centers for Disease Control and Prevention. "Immunization for Adults with Weakened Immune Systems." www.cdc.gov/vaccines/adults/immunization-adults-with-weak-immune-system.html.