What body functions does tigecycline affect?

What body functions does tigecycline affect?

Tigecycline is an antibiotic that works by disrupting bacterial protein production. It targets the bacterial ribosome, preventing the bacteria from making the proteins they need to grow and survive. That core mechanism affects the body indirectly by stopping infection-causing bacteria, rather than by directly changing human organ systems’ functions. [1]

Which human body systems are affected indirectly (and which aren’t)?

Tigecycline’s intended action is against bacteria, so it doesn’t selectively “affect” specific human body functions the way a hormone or pain medicine would. Effects on the body you may notice are mainly the result of either (1) treating an infection or (2) side effects from the medication itself, which can involve the gastrointestinal tract and other systems commonly seen with antibiotics. [1]

What’s the key mechanism behind how it affects bacteria?

Tigecycline binds to the bacterial ribosome and blocks protein synthesis. By shutting down that process, it halts bacterial growth and can help clear the infection. [1]

Where do people notice effects during treatment?

Because tigecycline is used to treat certain bacterial infections, people typically notice changes related to infection improvement (such as reduced symptoms) and antibiotic side effects (for example, gastrointestinal symptoms are commonly reported with this class of drugs). Those experiences still stem from the drug being an antibacterial agent and its effects on the body as a medication, not from direct targeting of specific human body functions. [1]

Source

1. https://www.drugs.com/tigecycline.html