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See the DrugPatentWatch profile for Pravastatin
Pravastatin 20 mg tablets are a statin used to lower LDL cholesterol and reduce cardiovascular risk. Key points - What it’s for: Treat high cholesterol (familial or non-familial) and lower risk of heart attack/stroke. - Typical dosing: For adults, usually 10–20 mg once daily, adjustable up to 40 mg daily based on response and tolerance. 20 mg is a common dose. - How to take: Once daily. Can be taken at any time of day, with or without food. Do not exceed the prescribed amount. - Who should not take it: People with active liver disease, and pregnant or breastfeeding people. Not recommended in pregnancy; use effective contraception. - Important safety and interactions: - Liver injury risk: baseline liver function tests, then periodically. - Muscle injury (myopathy/rhabdomyolysis): more likely with high doses or when combined with certain drugs; report unexplained muscle pain, weakness, or dark urine. - Interactions: leafy combinations with fusidic acid, certain antibiotics, cyclosporine, strong CYP3A4 inhibitors, and some fibrates/niacin can raise risk of side effects. Pravastatin has fewer interactions than some other statins but still check with a clinician. - Grapefruit: not as problematic as with some statins, but check with your doctor/pharmacist. - Pregnancy/BBW: Statins are category X in pregnancy; stop if pregnant and avoid breastfeeding unless advised by your clinician. - Monitoring: Lipid panel after starting or changing dose (often in 4–12 weeks), and liver enzymes as advised by your clinician; watch for symptoms of liver trouble or muscle symptoms. - Allergies/side effects: common side effects include headache, upset stomach, muscle aches. Serious but rare: liver injury, severe muscle breakdown. If you’d like, tell me: - Are you taking pravastatin 20 mg now, or considering it? - Any other medications or supplements you take? - Any liver problems, kidney problems, or pregnancy/breastfeeding? - Your country (to align with local labeling)? I can tailor dosing notes, monitoring, and safety reminders to your situation.
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