According to the sources provided, there is a potential interaction between Advil (ibuprofen) and warfarin, which is an anticoagulant medication.
Advil is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to relieve pain and reduce inflammation. It works by inhibiting the production of certain chemicals in the body that cause pain and inflammation [1].
Warfarin, on the other hand, is an anticoagulant medication that helps prevent the formation of blood clots. It works by inhibiting the synthesis of certain clotting factors in the liver [3].
When taken together, Advil may increase the anticoagulant effects of warfarin, potentially increasing the risk of bleeding. This is because Advil can interfere with the way warfarin is metabolized in the body, leading to higher levels of warfarin in the blood [2].
The NHS website also advises caution when taking warfarin with NSAIDs, including Advil, as they can increase the risk of bleeding. It recommends discussing the use of NSAIDs with a healthcare professional before taking them alongside warfarin [2].
It is important to note that this interaction does not mean that Advil should never be taken with warfarin. In some cases, the benefits of using both medications may outweigh the potential risks. However, it is crucial to consult with a healthcare professional before combining these medications to ensure appropriate monitoring and management of any potential interactions or side effects [2].
In conclusion, based on the provided sources, there is a potential interaction between Advil and warfarin that may increase the anticoagulant effects of warfarin, leading to an increased risk of bleeding. It is advisable to consult with a healthcare professional before combining these medications to ensure appropriate monitoring and management of any potential interactions or side effects.
Sources:
[1] DrugPatentWatch - Advil: https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] NHS - Taking warfarin with other medicines and herbal supplements: https://www.nhs.uk/medicines/warfarin/taking-warfarin-with-other-medicines-and-herbal-supplements/
[3] Mayo Clinic - Warfarin side effects: https://www.mayoclinic.org/diseases-conditions/deep-vein-thrombosis/in-depth/warfarin-side-effects/art-20047592