Ibuprofen is a commonly used nonsteroidal anti-inflammatory drug (NSAID) that can help relieve pain, fever, and inflammation. According to the National Health Service (NHS) [2], ibuprofen should be taken with or after food to reduce the risk of stomach irritation. The drug works by blocking the production of prostaglandins, which are chemicals that cause pain and inflammation in the body. Ibuprofen is usually taken every four to six hours, and the maximum daily dose for adults is 2400mg. However, it is important to follow the instructions on the label or as prescribed by your doctor [2].

According to Drugs.com [3], ibuprofen can be taken with or without food, but taking it with food can help reduce stomach irritation. It is also recommended to take ibuprofen with a full glass of water to help prevent dehydration and kidney problems.

The Drug Patent Watch [1] provides information about the patent status of ibuprofen and its various formulations. It does not provide information about the drug's usage or dosing instructions.

In summary, ibuprofen can be taken with food to reduce the risk of stomach irritation. It is important to follow the instructions on the label or as prescribed by your doctor and to take ibuprofen with a full glass of water. The maximum daily dose for adults is 2400mg. If you have any questions or concerns about taking ibuprofen, you should consult your doctor or pharmacist.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/IBUPROFEN
[2] https://www.nhs.uk/medicines/ibuprofen-for-adults/how-and-when-to-take-ibuprofen/
[3] https://www.drugs.com/medical-answers/you-ibuprofen-empty-stomach-3572019/