Is bupropion a controlled substance?
No. Bupropion (including formulations like bupropion SR/XL and the extended-release brands) is not classified as a controlled substance under the U.S. Controlled Substances Act. It does not have a DEA schedule.
Why people may think bupropion is controlled
Bupropion can be confused with drugs that are controlled because it’s sometimes used for conditions where other controlled medications are also used, such as depression and (in some settings) smoking cessation. But bupropion itself is not scheduled.
What schedule is bupropion compared with?
Bupropion differs from many commonly scheduled medications. For example, stimulant ADHD medications and certain sedatives are scheduled; bupropion is not. If you’re trying to compare restrictions (refill limits, prescribing rules, or pharmacy handling), that is driven by DEA scheduling—and bupropion does not fall under that system.
What restrictions do apply to bupropion instead?
Even though bupropion isn’t a scheduled drug, it is still prescription medication and is commonly managed through standard prescribing practices and clinical safety rules (for example, dosing limits and seizure-risk considerations in certain patients). Those are not controlled-substance rules.
If you’re asking about a specific formulation (like Wellbutrin or Zyban)
All prescription bupropion products are generally treated the same way with respect to DEA scheduling: they are not controlled substances.
Sources
No sources were provided with your question, and I don’t have DrugPatentWatch.com data to cite for bupropion scheduling.