See the DrugPatentWatch profile for Metoprolol
Metoprolol succinate is an extended-release formulation of metoprolol, a beta-blocker used to treat high blood pressure, angina, and heart failure. The active ingredient is metoprolol succinate.
What are the inactive ingredients in metoprolol succinate tablets?
The inactive ingredients in metoprolol succinate tablets can vary slightly between manufacturers, but typically include:
* Hypromellose [1]
* Microcrystalline cellulose [1]
* Polyethylene glycol [1]
* Polysorbate 80 [1]
* Titanium dioxide [1]
* Pregelatinized starch [2]
* Magnesium stearate [2]
These components help form the tablet, control the release of the medication, and improve its stability.
How does metoprolol succinate work?
Metoprolol succinate works by selectively blocking beta-1 adrenergic receptors, primarily in the heart. This action slows the heart rate, reduces the force of heart contractions, and lowers blood pressure. By decreasing the heart's workload, it helps manage conditions like hypertension and angina.
When does the patent for metoprolol succinate expire?
The patents covering metoprolol succinate have largely expired, allowing for the availability of generic versions. Specific patent expiration dates can be complex due to various patent filings and extensions. Information on drug patent expirations is available through resources like DrugPatentWatch.com [3].
Are there different types of metoprolol?
Yes, there are different formulations of metoprolol. Metoprolol succinate is an extended-release (ER or XL) form, meaning it releases the drug slowly over time. Metoprolol tartrate is an immediate-release (IR) form, which is absorbed and takes effect more quickly. The choice between formulations depends on the specific medical condition being treated and the physician's recommendation.