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What does a vial of Syndros cost? A 300‑mcg vial of Syndros is listed at roughly $1,500 in most U.S. pharmacies. This is the wholesale or manufacturer‑set price that pharmacies pay before any insurer discounts or rebates [1]. How much does a typical chemotherapy course cost? A 5‑day course (one vial per day) usually runs about $7,500, while a 10‑day course can reach roughly $15,000. These figures assume the patient receives the drug daily at the listed price and do not include infusion costs or other chemotherapy supplies [2]. Are there rebates or discounts that lower the price for hospitals? Hospitals often negotiate volume‑based rebates that can bring the effective price down by 10‑20 %. However, the exact reduction varies by payer contract and the institution’s bargaining power. In 2023, reported rebates for Syndros ranged from $100 to $200 per vial in some hospital networks [3]. How does Syndros compare to the original drug Neupogen? Neupogen’s average wholesale price is around $1,700 per vial, so Syndros is about 12 % cheaper on the shelf. After typical rebates, the price gap can narrow to less than $100 per vial, depending on the pharmacy or hospital agreement [4]. What Medicare pays for Syndros under Part B? Medicare Part B reimburses about $1,200 per vial for filgrastim products, including Syndros, after applying the federal drug discount. The actual payment may be a few dollars lower due to administrative fees, but it stays near the $1,200 mark for most claims [5]. Do insurers cover the full cost of Syndros? Most commercial insurers include filgrastim under their oncology or supportive‑care formularies and cover the drug after a standard co‑payment or deductible. Patients with high‑deductible plans may face out‑of‑pocket costs of up to $1,000–$1,200 per vial if no co‑payment is applied [6]. Is there a patient assistance program for Syndros? Amgen offers a patient
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