Methotrexate is a commonly prescribed medication used to treat various conditions such as rheumatoid arthritis, psoriasis, and certain types of cancer [1]. While methotrexate can be an effective treatment option, it can also cause several side effects. Here are some ways to manage methotrexate side effects:
1. Monitor liver function: Methotrexate can cause liver damage, so it's essential to have regular liver function tests while taking this medication [1]. If liver enzymes become elevated, your doctor may adjust your dosage or recommend a different treatment.
2. Stay hydrated: Methotrexate can cause kidney damage, so it's crucial to drink plenty of fluids while taking this medication [1]. This can help flush the medication out of your system and reduce the risk of kidney damage.
3. Manage nausea and vomiting: Methotrexate can cause nausea and vomiting, which can lead to dehydration [1]. Your doctor may prescribe anti-nausea medication or recommend over-the-counter options to help manage these side effects.
4. Take folic acid: Methotrexate can deplete folic acid levels in the body, which can lead to anemia, fatigue, and other side effects [1]. Taking a folic acid supplement can help prevent these side effects.
5. Avoid alcohol: Alcohol can increase the risk of liver damage and other side effects associated with methotrexate [1]. It's best to avoid alcohol while taking this medication.
6. Report unusual symptoms: Methotrexate can cause rare but serious side effects, such as lung toxicity and severe skin reactions [1]. It's essential to report any unusual symptoms to your doctor immediately.
It's important to note that the best way to manage methotrexate side effects is to work closely with your healthcare provider. They can help monitor your symptoms, adjust your dosage, and recommend additional treatments as needed.
Sources:
1. "[Methotrexate Sodium (Injection)](https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=6d3a6e3a-8e4e-4a7f-a1f3-80b6e1e1b27d&type=display)" (U.S. National Library of Medicine)