How many neffy sprays are in one device?

Neffy Sprays per Device

One Neffy autoinjector contains two 2 mg doses of epinephrine nasal spray, delivered as two separate sprays.[1]

How Neffy Dosing Works

Neffy delivers 2 mg of epinephrine per spray (0.3 mL volume). For anaphylaxis, administer one spray into one nostril. If symptoms persist after 5 minutes, use the second spray in the opposite nostril. The device is single-patient use only.[1][2]

Neffy vs. EpiPen Comparison

| Device | Doses per Device | Epinephrine per Dose | Delivery Method |
|--------|------------------|----------------------|-----------------|
| Neffy | 2 | 2 mg | Nasal spray |
| EpiPen| 2 | 0.3 mg | Intramuscular injection |

Neffy uses a higher dose but nasal route, approved for patients weighing 30 kg or more.[1][3]

Availability and Pricing

Neffy comes in a carton with one or two autoinjectors. List price is about $6,500 for a two-pack, though copay cards reduce patient costs to $25 or less.[4]

Storage and Expiration

Store at 20-25°C (68-77°F); usable up to 4 days at 49°C (120°F). Check expiration date on label; typical shelf life is 12-18 months.[1]

[1]: Neffy Prescribing Information
[2]: FDA Approval Summary
[3]: EpiPen Prescribing Information
[4]: GoodRx Neffy Pricing