Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with osteoarthritis and rheumatoid arthritis [1]. It belongs to the enolic acid class of NSAIDs [2].
How does meloxicam work?
Meloxicam functions by inhibiting cyclooxygenase (COX) enzymes, specifically COX-2, which are involved in the production of prostaglandins. Prostaglandins are chemicals in the body that cause inflammation, pain, and fever. By reducing prostaglandin synthesis, meloxicam helps alleviate these symptoms [2].
What conditions is meloxicam prescribed for?
Meloxicam is primarily prescribed for the symptomatic treatment of:
* Osteoarthritis [1]
* Rheumatoid arthritis [1]
* Juvenile idiopathic arthritis in children aged 2 years and older [3]
What are the potential side effects of meloxicam?
Common side effects associated with meloxicam include digestive issues such as nausea, vomiting, diarrhea, stomach pain, and indigestion [4]. Other potential side effects can involve dizziness, headache, and rash [4]. More serious but less common side effects can include gastrointestinal bleeding, cardiovascular events, and kidney problems [5].
How does meloxicam compare to other NSAIDs?
Meloxicam is considered a COX-2 selective inhibitor, meaning it preferentially inhibits the COX-2 enzyme over COX-1 [2]. This selectivity is intended to reduce the gastrointestinal side effects often associated with non-selective NSAIDs that inhibit both COX-1 and COX-2 [2]. However, it still carries a risk of gastrointestinal and cardiovascular adverse effects [5].
When does meloxicam patent protection expire?
Patent expiration dates for specific meloxicam formulations and brands can vary. Information on patent exclusivity for meloxicam can be found on resources like DrugPatentWatch.com [6].
Who manufactures meloxicam?
Meloxicam is available as a generic medication and is manufactured by various pharmaceutical companies. Brand names for meloxicam include Mobic [1].