Hydrogenated soy phosphatidylcholine composition dspc dppc?

Hydrogenated Soy Phosphatidylcholine (HSPC) is not a single, chemically defined compound but a mixture of hydrogenated soybean‑derived phosphatidylcholines.
The bulk of the mixture consists of saturated phosphatidylcholines that have two saturated acyl chains. The two most abundant species are:

| Species | Acyl chains | Phase‑transition temperature (T_m) | Typical % in commercial HSPC |
|---------|-------------|---------------------------------------------|------------------------------|
| DSPC (distearoyl‑phosphatidylcholine) | 18:0 + 18:0 | ~53 °C | ~50–60 % |
| DPPC (dipalmitoyl‑phosphatidylcholine) | 16:0 + 16:0 | ~41 °C | ~20–30 % |
| Other saturated PCs (e.g., dipalmitoyl‑phosphatidylglycerol, dipalmitoyl‑phosphatidylinositol, etc.) | 16–18:0 + 16–18:0 | 30–45 °C | ~10–20 % |

Key points
• DSPC and DPPC dominate the composition and are responsible for the high phase‑transition temperatures that give HSPC‑based liposomes their stability at body temperature.
• The exact ratio can vary by manufacturer and batch, but most commercial preparations fall within the ranges above.
• The “other” saturated PCs contribute minor amounts of diversity to the fatty‑acid composition and can slightly modulate the fluidity and packing of the bilayer.

If you need the exact specification for a particular product (e.g., from a vendor like Avanti Polar Lipids, Lipoid, or Gattefossé), you should refer to the product’s technical datasheet. The datasheets usually list the composition as a percentage of DSPC, DPPC, and any other phospholipids present.