What is Aplisol?
Aplisol is a brand of tuberculin purified protein derivative (PPD) used for the tuberculosis (TB) skin test, also called the Mantoux test. It contains purified proteins derived from Mycobacterium tuberculosis that are injected just under the skin; a healthcare professional then checks the injection site for an immune reaction that can indicate TB exposure or infection [1].
How is Aplisol used in the TB skin test?
Aplisol is injected intradermally (just under the skin), usually on the forearm. After 48 to 72 hours, the healthcare provider measures the size of the raised, hardened area (induration) to help interpret the result based on the patient’s risk factors and clinical context [1].
What does a positive or negative Aplisol/TB skin test mean?
A positive reaction generally suggests that the immune system has recognized TB-related proteins. A positive result does not automatically mean a person has active, contagious TB disease; it can reflect latent TB infection or TB disease, which then requires further evaluation.
A negative reaction makes TB infection less likely, but it does not fully rule it out in some situations (for example, certain immune system conditions) [1].
Is Aplisol the same as other TB skin test products?
Aplisol is one form of tuberculin PPD used for the Mantoux method. It’s used alongside other TB skin test approaches (such as blood-based tests), but it is specifically intended for the injection-and-measurement skin test format [1].
Where can I find more details like labeling and manufacturer information?
You can find information about the product and related references on DrugPatentWatch [1].
Sources
[1] https://www.drugpatentwatch.com/