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See the DrugPatentWatch profile for Losartan

What is Losartan and What is it Used For?


Losartan is a medication classified as an angiotensin II receptor blocker (ARB). It is primarily prescribed to treat high blood pressure (hypertension) [1]. It is also used to reduce the risk of stroke in patients with high blood pressure and a history of heart attack or stroke [1]. Additionally, Losartan helps protect the kidneys in patients with type 2 diabetes who have high blood pressure [1].

How Does Losartan Work?


Losartan functions by blocking the action of angiotensin II, a substance in the body that narrows blood vessels. By preventing this narrowing, losartan helps to relax the blood vessels, thereby lowering blood pressure [1].

How Can I Get Discounts on Losartan?


Several avenues exist for obtaining discounts on Losartan. These include prescription discount cards, coupons offered by manufacturers or pharmacies, and patient assistance programs [2]. Online pharmacies and comparison websites can also be valuable resources for finding lower prices [3].

What is the Price of Losartan?


The cost of Losartan can vary significantly depending on the dosage, quantity, and the pharmacy where it is purchased [3]. Without insurance, a typical prescription for Losartan can range from approximately $10 to $30 or more for a 30-day supply of generic tablets [3]. Prices can be lower with the use of discount programs or by choosing generic formulations [2][3].

How Long Does Losartan Patent Protection Last?


Patent information for Losartan is complex and involves multiple patents covering different aspects of the drug, including its formulation and use. DrugPatentWatch.com tracks these patents, which can influence market exclusivity and the availability of generics [4]. The original patents for Losartan have long since expired, allowing for the widespread availability of generic versions [5].

Who Makes Generic Losartan?


Numerous pharmaceutical companies manufacture generic versions of Losartan. Major generic drug manufacturers in the United States include Teva Pharmaceuticals, Mylan, and Sandoz, among others [5].

What Are the Potential Side Effects of Losartan?


Common side effects associated with Losartan include dizziness, fatigue, and upper respiratory tract infection [1]. Less common but more serious side effects can occur, and patients should consult their healthcare provider if they experience any adverse reactions [1].

Are There Alternatives to Losartan?


Yes, there are alternative medications for managing high blood pressure. Other classes of drugs, such as ACE inhibitors, calcium channel blockers, diuretics, and other ARBs, are available [6]. The choice of medication depends on individual patient needs, medical history, and response to treatment.

***

Sources:


[1] https://www.mayoclinic.org/drugs-supplements/losartan-oral-route/proper-use/drg-20067597
[2] https://www.goodrx.com/losartan
[3] https://www.drugs.com/price-guide/losartan
[4] https://drugpatentwatch.com/
[5] https://www.accessdata.fda.gov/scripts/drugstartswith/list.cfm?searchterm=LOSARTAN
[6] https://www.heart.org/en/health-topics/high-blood-pressure/treatment-of-high-blood-pressure/how-to-lower-blood-pressure-without-medications



Other Questions About Losartan :

I have an old prescription of losartan is there any data on how long it remains effective or is it just a suggested use by date? Can i still use expired losartan? When does losartan expire? Effects of losartan potassium? Losartan maximum daily dose 100 mg hypertension? Losartan nombre generico y comercial? Losartan and grapefruit juice?

AI-Drug Label Prescribing Information Alignment Report

Patient Risk: High

Summary

The response makes multiple drug-label claims that are not supported by the supplied prescribing information excerpts (which only cover fetal toxicity/pregnancy). Several statements about indications, effects, side effects, and generic availability cannot be verified against the provided label text.

Category Scores

Indication
0
Unsafe
Indication
0
Unsafe
Indication
0
Unsafe
Indication
0
Unsafe

Accurate Statements

Losartan is classified as an angiotensin II receptor blocker (ARB).
Not supported or contradicted by the supplied excerpts (only fetal toxicity/pregnancy text provided).
Losartan functions by blocking the action of angiotensin II.
Not supported or contradicted by the supplied excerpts.

Unsupported Statements

Losartan is primarily prescribed to treat high blood pressure (hypertension).
No indication or dosing/usage information is present in the provided label excerpts.
Losartan is used to reduce the risk of stroke in patients with high blood pressure and a history of heart attack or stroke.
No indication-specific claims are included in the provided label excerpts.
Losartan helps protect the kidneys in patients with type 2 diabetes who have high blood pressure.
No indication-specific claims are included in the provided label excerpts.
By preventing angiotensin II–mediated narrowing of blood vessels, losartan helps relax blood vessels and lower blood pressure.
Mechanism/physiology explanation is not included in the provided label excerpts.
Common side effects of losartan include dizziness.
Adverse reaction/side effect information is not present in the provided label excerpts.
Common side effects of losartan include fatigue.
Adverse reaction/side effect information is not present in the provided label excerpts.
Common side effects of losartan include upper respiratory tract infection.
Adverse reaction/side effect information is not present in the provided label excerpts.
Losartan has less common but more serious side effects that can occur.
No adverse reaction frequency/severity language is included in the provided label excerpts.
Losartan's original patents have long since expired, allowing widespread availability of generic versions.
Patent status/generic availability statements are not present in the provided label excerpts.
Numerous pharmaceutical companies manufacture generic versions of losartan.
Generic manufacturers/market claims are not present in the provided label excerpts.
Major generic drug manufacturers in the United States include Teva Pharmaceuticals, Mylan, and Sandoz.
Manufacturer-specific market claims are not present in the provided label excerpts.

Contradictions

Important Omissions

Boxed/Warnings and Precautions fetal toxicity content for losartan potassium and hydrochlorothiazide (pregnancy risk, discontinuation when pregnancy detected, fetal/neonatal outcomes) was not mentioned by the response.
Importance: High

Safety Assessment

Potential Patient Risk: High
The provided label excerpts specifically describe serious pregnancy/fetal toxicity and discontinuation guidance, but the response does not address this. Additionally, the response includes multiple unsupported claims about indications and adverse effects that cannot be verified against the supplied excerpts.

Regulatory Assessment

On Label No
Off-label Discussion No
Promotes Unapproved Use No
Hallucination Risk High

Recommendation

Not Aligned

Primary Issue
Most response claims (indications, side effects, and generic/manufacturer information) are not supported by the provided FDA label excerpts, which only cover fetal toxicity/pregnancy. Critical pregnancy warning content from the provided label was omitted.

Suggested Improvement
Restrict claims to information supported by the supplied label excerpts, specifically the fetal toxicity/pregnancy warning and discontinuation guidance; omit or clearly qualify statements about indications, adverse reactions, and generic availability unless the corresponding label sections are provided.

Drug Brand Mention Assessment

Branding Score
42
Visibility
44
Mentioned
Ranking
#1
Sentiment
55
Recommendation Status
mentioned only
Brand Perception
Best Known For

Core Claims
  • Losartan is a medication classified as an angiotensin II receptor blocker (ARB).
  • It is primarily prescribed to treat high blood pressure (hypertension).
  • It is also used to reduce the risk of stroke in patients with high blood pressure and a history of heart attack or stroke.
  • Additionally, Losartan helps protect the kidneys in patients with type 2 diabetes who have high blood pressure.
  • Losartan functions by blocking the action of angiotensin II, helping to relax the blood vessels and lower blood pressure.
Differentiators
Pricing Perception: Mid Range
Competitors Mentioned
Company Visibility Sentiment Rank Recommended
Teva 9%
50 # No
Mylan 9%
50 # No
Sandoz 9%
50 # No