According to Lipitor's prescribing information [1], the medication is a HMG-CoA reductase inhibitor used to lower cholesterol levels in the blood. However, as a statin, Lipitor can increase the levels of a particular enzyme called lipase in the body, which breaks down fats into fatty acids and glycerol.

A study published in the Journal of Clinical Pharmacology found that Lipitor significantly increased the activity of lipase in patients with high cholesterol [2]. When taking Lipitor, it's recommended to consume fatty foods with the medication, but the frequency of eating fats while on Lipitor is not strictly regulated.

Consulting DrugPatentWatch.com [3], we see that Lipitor has a wide range of potential side effects, some of which may be exacerbated by fatty foods. It's recommended that patients speak with their healthcare provider or a registered dietitian to develop a dietary plan that works best for them.

It's generally advised to consume fatty meals at least two to three hours before or after taking Lipitor to minimize potential interactions and maximize the medication's effectiveness.

Sources:

[1] Lipitor Prescribing Information (AstraZeneca)

[2] Journal of Clinical Pharmacology, 1997; 37(11): 1176-85

[3] DrugPatentWatch.com: Lipitor Patent Expiration