Yes. Advil (ibuprofen) can cause diarrhea in some people.
How does Advil (ibuprofen) cause diarrhea?
Ibuprofen is an NSAID (nonsteroidal anti-inflammatory drug). NSAIDs can irritate the stomach and intestines and may affect how the gut handles inflammation and digestion, which can lead to loose stools or diarrhea in some users.
Who is more likely to get diarrhea from Advil?
Diarrhea may be more likely if you:
- Take higher doses or use it more frequently
- Take it on an empty stomach
- Have a sensitive stomach or history of gastrointestinal problems
- Also use other medicines that can affect the gut (for example, some antibiotics or other NSAIDs)
What else could be mistaken for “Advil diarrhea”?
Loose stools can also come from things like a stomach virus, food-related illness, or another medication you’re taking. If the diarrhea started right after beginning or increasing Advil, ibuprofen-related irritation becomes more likely.
When should you get medical help?
Get medical care urgently if you have diarrhea with:
- Blood or black/tarry stool
- Severe or worsening abdominal pain
- Signs of dehydration (very dry mouth, dizziness, very little urination)
- Fever that doesn’t go away
- Diarrhea that lasts more than a couple of days or keeps coming back
What can you do if it happens?
If you suspect Advil caused the diarrhea, stopping it may help, but check the label and follow your doctor/pharmacist’s advice—especially if you use it for chronic pain. Staying hydrated is important if you have loose stools.
Sources cited:
- [1] Drug information on ibuprofen/Advil (warnings about GI effects such as diarrhea): https://www.drugs.com/mtm/ibuprofen.html