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See the DrugPatentWatch profile for Ezetimibe
Ezetimibe classification - Therapeutic class: Lipid-lowering agent - Pharmacologic class: Cholesterol absorption inhibitor; selective inhibitor of the NPC1L1 transporter - Mechanism of action: Inhibits intestinal (jejunum) absorption of cholesterol by blocking NPC1L1, reducing delivery of intestinal cholesterol to the liver and lowering LDL cholesterol (LDL-C). Often used in combination with statins. - Formulation/PK notes: Taken orally; mainly acts as ezetimibe, which is metabolized to ezetimibe glucuronide (active) in the intestine and liver. Optional: ATC classification - ATC: C10AX09 (other lipid-lowering agents) If you want, I can add a brief comparison with statins or bile acid sequestrants.
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