What is the shelf life of losartan?

Losartan—whether it’s the brand name Cozaar or any of the many generic tablets—has a typical shelf life of 2–3 years from the date of manufacture.

Key points

1. Check the expiration date on the packaging – that’s the official shelf life for that particular bottle. The date printed on the bottle is the last date that the manufacturer guarantees full potency and safety.
2. Store at room temperature (generally 20–25 °C or 68–77 °F). Avoid freezing, excessive heat, or high humidity; these conditions can accelerate degradation.
3. Do not use a drug past its expiration. While many patients report no noticeable difference, expired losartan may have reduced potency or, in rare cases, altered safety.
4. When in doubt, consult a pharmacist. They can confirm the drug’s status and advise on safe disposal if the medication has expired.

Regulatory guidance

• FDA and the United States Pharmacopeia (USP) list losartan potassium tablets with an expiration of 2–3 years when stored properly.
• European Medicines Agency (EMA) lists similar timelines for losartan generics.

If you have a specific bottle of losartan and are unsure whether it’s still safe, simply look at the expiration date printed on the bottle or on the inner label. If you’re ever uncertain, a pharmacist can confirm the product’s validity or advise on appropriate disposal.