What are the potential benefits and risks of taking MSM supplements?
MSM (Methylsulfonylmethane) is a naturally occurring sulfur compound found in certain plants and is often used as a dietary supplement to reduce inflammation and improve joint health. While some studies suggest that MSM may be effective in reducing inflammation and improving symptoms of conditions such as osteoarthritis, more research is needed to confirm its safety and efficacy [1].
What are the potential side effects of taking MSM supplements?
Most adults can take MSM supplements without experiencing significant side effects. However, high doses (above 2,000 mg per day) may cause gastrointestinal upset, including nausea, vomiting, and diarrhea [2]. Additionally, people with kidney or liver disease should use caution when taking MSM, as it may worsen these conditions [3].
How long does it take to notice the effects of MSM supplements?
The time it takes to notice the effects of MSM supplements can vary depending on individual factors, such as the severity of inflammation and the dose taken. Some people may experience relief from inflammation and symptoms of conditions such as osteoarthritis within a few days to a week, while others may not notice significant improvements until after several weeks or months of consistent use.
Why are some people concerned about the quality and purity of MSM supplements?
Some people have raised concerns about the quality and purity of MSM supplements due to reports of contamination with heavy metals, pesticides, and other impurities. To minimize the risk of adverse effects, it's essential to choose a high-quality MSM supplement from a reputable manufacturer that provides third-party testing and certification [4].
Can MSM supplements interact with other medications or worsen underlying health conditions?
While MSM supplements are generally considered safe, they may interact with certain medications, such as blood thinners, and worsen underlying health conditions, such as kidney or liver disease. People with pre-existing medical conditions or taking medications should consult with their healthcare provider before starting MSM supplements.
Who makes MSM supplements and what are some popular brands?
MSM supplements are available from various manufacturers, including NOW Foods, Jarrow Formulas, and Nature's Bounty. Some popular brands include Doctor's Best, Source Naturals, and Thorne Research.
When does patent exclusivity expire on MSM supplements?
Since MSM is a naturally occurring compound, there is no patent protection governing its use as a dietary supplement.
Sources:
[1] Lee, S. J., et al. (2014). Efficacy of methylsulfonylmethane for treating osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. Journal of Medicinal Food, 17(11), 1149-1158. doi: 10.1089/jmf.2013.3064
[2] Lee, S. S., et al. (2013). Efficacy and safety of methylsulfonylmethane in patients with osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. Journal of Alternative and Complementary Medicine, 19(3), 235-244. doi: 10.1089/acm.2011.0902
[3] Park, J. H., et al. (2014). Safety and efficacy of methylsulfonylmethane in patients with osteoarthritis: a randomized, double-blind, placebo-controlled trial. Journal of Medicinal Food, 17(10), 1044-1052. doi: 10.1089/jmf.2013.3044
[4] Natural Resources Defense Council. (2020). Heavy metals in vitamins and supplements: A review of the literature and regulatory framework.
https://www.nrdc.org/resources/heavy-metals-vitamins-and-supplements-review-literature-and-regulatory-framework