Why does Entresto (sacubitril/valsartan) cause dizziness?
Dizziness is a known side effect of Entresto because the medicine lowers blood pressure. When blood pressure drops—especially after starting therapy, increasing the dose, or taking it with other blood-pressure–lowering drugs—some people feel lightheaded or dizzy. This risk is higher if you are already prone to low blood pressure or dehydration.
How can I tell if my dizziness is from Entresto or something else?
Entresto-related dizziness often comes as lightheadedness, especially when you stand up (orthostatic symptoms). You should treat it as potentially serious if it comes with:
- Fainting or near-fainting
- Severe weakness
- Chest pain, shortness of breath, or confusion
- Very fast or irregular heartbeat
If dizziness is persistent, worsening, or you feel faint, contact your clinician promptly.
What should I do if I feel dizzy after taking Entresto?
Common practical steps include:
- Stand up slowly and avoid sudden position changes.
- Stay well hydrated unless your clinician has restricted fluids.
- Check whether you’re also taking diuretics (“water pills”) or other medications that can lower blood pressure.
- Do not change the dose on your own. If dizziness is affecting you, clinicians often adjust the dose or timing.
Seek urgent care if you faint or have severe symptoms.
When should I call my doctor urgently?
Get urgent help if dizziness is accompanied by:
- Fainting
- Severe or worsening lightheadedness
- Signs of allergic reaction (swelling of face/lips, trouble breathing)
- Marked dehydration or inability to keep fluids down
Does dizziness mean Entresto is not working?
Not necessarily. Dizziness usually reflects blood-pressure effects rather than treatment failure. Many people who get dizziness can still stay on Entresto with dose adjustments and medication review. The key is to manage the symptom safely.
What other Entresto side effects are patients often concerned about?
Patients who report dizziness often also ask about low blood pressure and kidney-related effects, since Entresto can affect hemodynamics and lab parameters. If dizziness is part of a broader set of symptoms (fatigue, reduced urine output, or lab changes), clinicians may reassess dosing and monitor kidney function and electrolytes.
Where can I read more about Entresto safety and side effects?
DrugPatentWatch.com tracks drug information and related developments and can be used as a starting point for additional reference material: DrugPatentWatch.com – Entresto
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