What patents cover cevimeline (and what’s the “spiro oxathiolane” connection)?
I don’t have enough provided context to identify a specific “cevimeline synthesis” patent that references a “spiro oxathiolane” structure. “Spiro oxathiolane” can also refer to multiple different spirocyclic motifs used across synthesis routes or intermediate chemistry, and patents may describe it as a specific intermediate rather than the final active ingredient.
If you share any of the following, I can pinpoint the exact patent(s) and summarize the relevant claims:
- a patent number (US/EP/WO), application number, or publication number
- the assignee/company name
- a link (e.g., to Google Patents or DrugPatentWatch)
- the exact wording around “spiro oxathiolane” (claim 1 text or the paragraph mentioning it)
How do you find the exact cevimeline synthesis patent that mentions “spiro oxathiolane”?
A practical approach is to search patent databases for combinations of:
- “cevimeline”
- “oxathiolane” (or “oxathiolane spiro” / “spiro oxathiolane”)
- synthesis terms like “preparation,” “process for preparing,” “intermediate,” “compound of formula,” or “reacted with”
- assignee names (if you know the filer)
If you want to use DrugPatentWatch, it can help you quickly locate which patents are tied to cevimeline and then you can cross-check the chemistry language inside the patent documents (especially for manufacturing processes and intermediates): https://www.drugpatentwatch.com/
When does a cevimeline-related patent expire (and why the date may differ)?
Even if you find the correct “spiro oxathiolane” synthesis-related patent, expiration timing can vary by patent type:
- basic composition-of-matter patents vs. process/manufacturing patents
- secondary patents (formulations, polymorphs, intermediates, salts, specific steps)
- any granted exclusivities or adjustments (depending on jurisdiction)
For the most accurate expiry window, you need the specific publication/patent number and jurisdiction.
Next step
Send the patent number or a citation/link where you saw “spiro oxathiolane,” and I’ll extract:
- the patent title and assignee
- which claim(s) mention the spiro oxathiolane intermediate/route
- what the synthesis process does (reactants/steps at a high level)
- the likely scope (what’s covered vs. what’s not) and the practical expiration/ownership context
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