Lurbinectedin is a chemotherapy drug used to treat certain types of cancer. According to the sources provided, hair loss and skin irritation are not commonly reported side effects of Lurbinectedin use. However, Lurbinectedin can cause other side effects, including nausea, vomiting, fatigue, anemia, and changes in blood cell counts [2]. It is important to note that everyone may react differently to chemotherapy drugs, and some people may experience different side effects than others. If you are concerned about hair loss or skin irritation while taking Lurbinectedin, it is recommended to talk to your doctor. They can provide you with more information about the potential side effects of Lurbinectedin and help you manage any side effects you may experience during treatment [3].

Sources:
[1] Drug Patent Watch. Lurbinectedin. Retrieved from https://www.drugpatentwatch.com/p/tradename/LURBINECTEDIN
[2] Mayo Clinic. Lurbinectedin (Intravenous Route): Side Effects. Retrieved from https://www.mayoclinic.org/drugs-supplements/lurbinectedin-intravenous-route/side-effects/drg-20490804?p=1
[3] ScienceDirect. Lurbinectedin. Retrieved from https://www.sciencedirect.com/topics/medicine-and-dentistry/lurbinectedin