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See the DrugPatentWatch profile for Losartan
For most adults, the typical starting “normal” dose of losartan is 50 mg once daily. Dosing is commonly adjusted based on the condition being treated and how the patient responds.
Dose decisions can change with: - Kidney function: clinicians may monitor labs and adjust dosing if kidney function is reduced. - Liver impairment: because losartan is processed in the liver, a lower starting dose is often used in people with significant hepatic impairment.
A commonly used upper limit in standard hypertension regimens is 100 mg once daily (depending on the indication and the prescriber’s plan).
Losartan is typically taken once daily, at about the same time each day. It can be taken with or without food.
People starting losartan often need extra caution and lab monitoring if they: - are pregnant (RAAS blockers like losartan are generally avoided in pregnancy) - have high potassium - have known kidney artery narrowing or a history of significant creatinine changes with similar medications
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