Follow Otrexup Instructions for Needle Disposal
Otrexup, an autoinjector for methotrexate used in rheumatoid arthritis and psoriasis, has a built-in safety mechanism. After injection, the needle automatically retracts into the device. Place the entire used Otrexup injector into a FDA-cleared sharps disposal container right away. Do not try to recap, bend, or break the needle—it's already shielded.[1]
What If You Don't Have a Sharps Container?
Use a heavy-duty plastic household container like a laundry detergent bottle. Ensure it's puncture-proof, leak-proof, and clearly labeled 'Home Sharps—Not for Recycling.' Seal it tightly with duct tape when 3/4 full, then dispose of it in your household trash following local rules. Never flush it or throw it loose in the trash.[1][2]
Local Rules and Mail-Back Options
Check your city's waste guidelines—some areas require drop-off at pharmacies, hospitals, or hazardous waste sites. Otrexup patients can use free mail-back programs from manufacturers or services like Sharps Compliance. Contact your pharmacy or visit the FDA's safe disposal locator for sites near you.[2][3]
Preventing Accidental Sticks and Kid/Pet Risks
Keep the container out of reach of children and pets. Lock it if possible. Full containers go to approved facilities, not curbside recycling or regular garbage unless locally allowed. For travel, carry a portable sharps container.[1][2]
[1] Otrexup Prescribing Information and Instructions for Use: https://www.otrexup.com/
[2] FDA Sharps Disposal Guidelines: https://www.fda.gov/medical-devices/safely-using-sharps-and-needles-home-work-and-travel/safe-disposal-sharps-used-home
[3] EPA Safe Needle Disposal: https://www.epa.gov/rcra/safe-needle-disposal