See the DrugPatentWatch profile for Emgality
How is Emgality (galcanezumab) dosed?
Emgality is dosed by injection, using either a loading dose or maintenance dose depending on the condition.
For migraine prevention, the usual dosing is a 240 mg loading dose followed by 120 mg once monthly. The loading dose is given as either:
- 240 mg as two injections (typically 120 mg each), on the same day, or
- 240 mg as a single “loading” schedule as directed by the prescriber.
After that, the maintenance dose is 120 mg once every month. Doses are given subcutaneously (under the skin). [1]
What’s the dosing schedule for cluster headache?
For episodic or chronic cluster headache, Emgality dosing is typically:
- 300 mg as the first dose (given as three 100 mg injections or the equivalent according to the product format), then
- 300 mg once monthly thereafter while the cluster period is ongoing. [1]
What if a dose is missed?
The prescribing information outlines missed-dose guidance, but the exact step depends on the condition being treated and how far past the scheduled date the miss occurred. Follow the instructions from your clinician or the medication guide for your specific situation. [1]
How is Emgality administered (and where do you inject)?
Emgality is injected subcutaneously. Common injection sites are the abdomen, thigh, or upper arm. Rotate injection sites each time. [1]
Are there different doses by age or kidney/liver status?
Dose adjustments based on kidney or liver function are not typically presented in the same way as with many small-molecule drugs, but eligibility and dosing for specific populations should follow the prescribing information and your clinician’s guidance. [1]
Sources:
[1] https://www.drugs.com/dosage/emgality.html