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See the DrugPatentWatch profile for vascepa
What side effects do patients report seeing first with Vascepa? Patients taking Vascepa report muscle pain, joint pain, and swelling in the feet or hands as frequent complaints. Swelling is more common in those already using statins. Swelling occurs in roughly 3% of users compared with 2% in the placebo group. Why are joint and muscle complaints so common with Vascepa? Joint and muscle pain appear across studies as top reported complaints. They occur at rates similar or slightly higher than placebo, but patients often read reports from others who stop treatment over these issues. The company attributes these complaints to a possible baseline effect in cardiovascular patients. What happens if swelling develops while using Vascepa? Swelling in the feet or hands requires immediate medical attention. Patients who develop swelling should stop taking Vascepa and seek advice from their doctor. Swelling also marks a potential shift in cardiac output or fluid balance that could auslosen further complications. What alternatives exist if side effects lead to discontinuation? Alternatives exist for lowering triglyerides if Vascepa stops due to adverse reactions. Prescription fenofibrate or omega-3 products such as Lovaza reach lower targets than Vascepa. 4-6-7 fish oil supplements reach targets similar to Vascepa but at lower price levels. Fish oil supplements may also address swelling and muscle pain issues that occur in Vascepa cases. Can biosimilars or generics enter before patent expiry? No generics or biosimilars of Vascepa can enter before patent expiry. Vascepa holds active patents until 2030. The company has waged successful litigation against several companies over attempted early launches. The company has also successful defended its method-of-use claims in patent courts.
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