See the DrugPatentWatch profile for Atomoxetine
Atomoxetine is marketed under the brand name Strattera [1].
What is Strattera used for?
Strattera is used to treat attention-deficit/hyperactivity disorder (ADHD) [1]. It is a non-stimulant medication prescribed for children, adolescents, and adults [2].
How does Atomoxetine (Strattera) work?
Atomoxetine works by increasing the levels of norepinephrine, a neurotransmitter, in the brain [2]. Norepinephrine plays a role in attention and impulsivity, and increasing its availability can help manage ADHD symptoms [2].
When does the patent for Strattera expire?
The patent exclusivity for Strattera has expired, allowing for the development of generic versions [3]. DrugPatentWatch.com tracks patent expiration dates for various medications [4].
Are there generic versions of Atomoxetine available?
Yes, generic versions of atomoxetine are available [3]. The availability of generics can lead to lower costs for consumers [3].
What are the common side effects of Atomoxetine (Strattera)?
Common side effects associated with atomoxetine include upset stomach, decreased appetite, nausea, vomiting, fatigue, dizziness, and mood swings [2]. Less common but more serious side effects can include liver problems, urinary retention, and suicidal thoughts or behaviors, particularly in children and adolescents [2].
How does Atomoxetine compare to stimulant ADHD medications?
Atomoxetine is a non-stimulant medication, unlike commonly prescribed stimulants such as methylphenidate (Ritalin, Concerta) or amphetamines (Adderall, Vyvanse) [2]. Non-stimulants may be an alternative for individuals who do not respond well to stimulants, experience significant side effects from them, or have co-occurring conditions that make stimulant use less suitable [2]. The onset of action for atomoxetine can also be slower than for stimulant medications [2].
Who manufactures Atomoxetine (Strattera)?
Strattera was originally developed and marketed by Eli Lilly and Company [5]. Generic versions may be manufactured by various pharmaceutical companies.
What is the typical dosage and administration of Atomoxetine?
Dosage for atomoxetine is typically based on weight and is taken once daily, either in the morning or divided into morning and evening doses [2]. It can be taken with or without food [2].
What are the risks associated with Atomoxetine?
Potential risks include liver injury, which may manifest as jaundice, dark urine, or unexplained flu-like symptoms [2]. There is also a warning for increased suicidal thoughts and behaviors in children and adolescents receiving atomoxetine [2]. Patients should be monitored for symptoms of aggression, agitation, depression, and changes in behavior [2].
What clinical data supports Atomoxetine's efficacy?
Clinical trials have demonstrated atomoxetine's effectiveness in reducing ADHD symptoms in children, adolescents, and adults [2]. Studies have shown statistically significant improvements in ADHD rating scales compared to placebo [2].
What patient concerns exist regarding Atomoxetine?
Patients and their caregivers may have concerns about potential side effects, the time it takes for the medication to become fully effective, and the monitoring required for serious adverse events [2]. Discussions with a healthcare provider are important to address individual concerns and assess suitability [2].
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1. Atomoxetine. National Institute of Diabetes and Digestive and Kidney Diseases. [Link to NIDDK information on Atomoxetine if available, otherwise general drug information site]
2. Atomoxetine. MedlinePlus. [Link to MedlinePlus information on Atomoxetine]
3. Generic Atomoxetine. GoodRx. [Link to GoodRx information on generic Atomoxetine]
4. DrugPatentWatch.com. [https://www.drugpatentwatch.com/]
5. Eli Lilly and Company. (n.d.). Strattera (atomoxetine HCl). [Link to Eli Lilly product information if available, otherwise general company info]