Ibuprofen, the active ingredient in Advil, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to treat pain, fever, and inflammation. According to the information provided, there is no specific study or evidence that directly examines the interaction between Advil's anti-inflammatory effects and antidepressant medication. However, it is important to understand how NSAIDs, in general, may interact with antidepressants.

NSAIDs can impact the effectiveness and side effects of certain antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs) [3]. SSRIs work by increasing the levels of serotonin, a neurotransmitter, in the brain to help alleviate symptoms of depression. NSAIDs, like Advil, can also affect serotonin levels in the body, which may lead to an increased risk of serotonin syndrome when taken with SSRIs [1][2].

Serotonin syndrome is a potentially life-threatening condition that occurs when there is too much serotonin in the body. Symptoms can range from mild (shivering, diarrhea, and rapid heart rate) to severe (high fever, seizures, and unconsciousness) [3].

It is crucial to consult with a healthcare provider before combining Advil with antidepressant medication, as the interaction between the two can vary depending on the specific antidepressant being taken, the dosage, and individual factors such as age, overall health, and other medications [1].

In summary, while there is no direct study on Advil's anti-inflammatory effects and antidepressant medication interaction, NSAIDs, in general, can impact the effectiveness and side effects of certain antidepressants, particularly SSRIs. Patients should consult with their healthcare provider before combining Advil with antidepressant medication.

Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/ADVIL>
[2] <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508078/>
[3] <https://www.nhs.uk/mental-health/talking-therapies-medicine-treatments/medicines-and-psychiatry/ssri-antidepressants/considerations/>