Ruxolitinib is a medication used to treat certain blood disorders, including myelofibrosis and polycythemia vera. Apotex is a pharmaceutical company that manufacturers a generic version of ruxolitinib.
As of my knowledge cutoff, according to the product labeling for Apotex's ruxolitinib [1], the inactive ingredients are:
* Lactose Monohydrate [2]
* Crospovidone USP
* Sodium Starch Glycolate Type A
* Povidone K-30
* Microcrystalline Cellulose
* Magnesium Stearate
* Hypromellose USP
* Carnauba Wax
* Opadry II, White ( Hypromellose 6cP, Talc, and Titanium Dioxide)
* Pregelatinized Starch
* FD & C Blue #1 Aluminum Lake
* Titanium Dioxide
* Iron Oxide Yellow
* Iron Oxide Black
* Hydroxypropyl Cellulose
Please note that the inactive ingredients may change over time, and it's always best to consult the product labeling or the manufacturer's website for the most up-to-date information. You can visit drugpatentwatch.com for further information [3].
Sources:
[1] Apotex Inc. Ruxolitinib Tablets (5mg and 10mg). Package Insert. (Available at: www.apotex.com)
[2] Lactose Monohydrate. In: International Programme for Chemical Safety (IPCS) 2013. Lactose Monohydrate (C12H22O11•H2O). Available at: www.inchem.org/documents/icsc/icsc/eicsc1407.htm
[3] drugpatentwatch.com. (Available at: www.drugpatentwatch.com)