Tigecycline, sold under the brand name Tygacil, is an antibiotic used to treat various bacterial infections. While generally well-tolerated, it can cause some serious side effects. According to information from Pfizer Medical Information, some of the severe adverse reactions associated with tigecycline include an increased risk of death, especially when used to treat serious infections. Additionally, the drug can lead to Clostridium difficile-associated diarrhea, which is a severe intestinal condition. Other serious side effects can include liver problems, allergic reactions like anaphylaxis, and potential effects on fetal development if used during pregnancy. It is essential to consult with a healthcare provider if any concerning symptoms occur while taking tigecycline to address them promptly and ensure safe use of the medication [3].

Sources:
[3] https://www.pfizermedicalinformation.com/tygacil/adverse-reactions