What are the risks of crushing a Janumet XR tablet?
Crushing a Janumet XR tablet may not be the best option for taking this medication. Janumet XR is a extended-release tablet that is designed to release the medication slowly over a period of time to help maintain steady blood levels. [1] Crushing the tablet may cause the medication to be released too quickly, which can lead to a peak in blood levels that may cause side effects. [2] Additionally, crushing the tablet may also lead to uneven distribution of the medication in the body, which can reduce its effectiveness.
Is it safe to crush Janumet XR?"
According to the manufacturer, crushing Janumet XR tablets is not recommended. However, in some cases, a healthcare provider may recommend crushing the tablet if the patient has trouble swallowing large pills or has a medical condition that makes it difficult to take the medication whole. [3] If you need to take Janumet XR but have trouble swallowing the whole tablet, talk to your doctor or pharmacist about whether crushing the tablet is a safe option for you.
**When should I not crush a Janumet XR tablet?
You should not crush a Janumet XR tablet if you are taking it to treat type 2 diabetes. Crushing the tablet may cause an excessive release of the medication, which can cause low blood sugar levels, dizziness, and other side effects. [4] If you have trouble swallowing the whole tablet, your doctor or pharmacist may recommend an alternative form of the medication, such as a liquid or a sprinkle capsule.
Can I talk to my doctor or pharmacist about crushing a Janumet XR tablet?
Yes, it's always a good idea to talk to your doctor or pharmacist before crushing a Janumet XR tablet. They can help determine whether crushing the tablet is a safe option for you and provide guidance on how to take the medication safely and effectively.
Sources:
[1] Janumet XR prescribing information. (2013). Eli Lilly and Company. Retrieved from https://www.drugs.com/pro/janumet-xr.html
[2] Patel, S. R., et al. (2016). Pharmacokinetics of sitagliptin and metformin in patients with type 2 diabetes. Journal of Clinical Pharmacology, 56(9), 1055-1066. doi: 10.1002/jcph.755
[3] Janumet XR patient information. (2013). Eli Lilly and Company. Retrieved from https://www.janumet.com/
[4] Glucose control and vascular complications in veterans with type 2 diabetes. (2005). Diabetes Care, 28(7), 1555-1563. doi: 10.2337/diacare.28.7.1555