Based on the information available, there is no definitive evidence to suggest that Lipitor, a medication used to treat high cholesterol, interferes with the effectiveness of antibiotics.

Lipitor, also known as atorvastatin, is a type of drug known as a statin, which lowers cholesterol levels in the body. Antibiotics, on the other hand, are used to treat infections caused by bacteria.

While both Lipitor and antibiotics can be taken together, it is always important to inform your healthcare provider of all medications, supplements, and over-the-counter products you are taking, as there can be potential drug interactions.

It is also worth noting that while there is no evidence to suggest that Lipitor directly interferes with antibiotic effectiveness, there is some evidence to suggest that statins, such as Lipitor, can have an impact on the immune system. However, this is not necessarily related to antibiotic effectiveness.

In conclusion, while it is always important to inform your healthcare provider of all medications you are taking, there is no current evidence to suggest that Lipitor directly interferes with the effectiveness of antibiotics.

Sources:
[1] <https://www.drugs.com/drug-interactions/atorvastatin-with-amoxicillin-2036-1173-144-931333.html>
[2] <https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statins/art-20045935>
[3] <https://www.drugpatentwatch.com/drugs/lipitor>