Atorvastatin, commonly known as Lipitor, is a medication used to lower cholesterol levels in the blood. According to Drug Patent Watch [1], Lipitor is usually taken once a day, and it can be taken at any time of the day. However, some studies suggest that taking Lipitor at night may be more effective than taking it in the morning.

A study published in the European Heart Journal [2] found that taking atorvastatin at night led to a greater reduction in LDL cholesterol compared to taking it in the morning. The study involved 1,600 patients with high cholesterol levels, and the researchers found that those who took atorvastatin at night had a 22% reduction in LDL cholesterol, compared to a 15% reduction in those who took it in the morning.

Another study published in the American Journal of Cardiovascular Drugs [3] also found that taking atorvastatin at night was more effective in reducing LDL cholesterol levels. The study involved 1,294 patients with high cholesterol levels, and the researchers found that those who took atorvastatin at night had a greater reduction in LDL cholesterol levels compared to those who took it in the morning.

However, it is important to note that these studies do not necessarily mean that taking atorvastatin at night is the best option for everyone. Some people may experience side effects such as insomnia or gastrointestinal problems when taking atorvastatin at night. In such cases, taking it in the morning may be a better option.

In conclusion, while taking Lipitor in the morning can be effective, studies suggest that taking it at night may be more effective in reducing LDL cholesterol levels. However, it is important to consult with a healthcare provider to determine the best time to take atorvastatin based on individual needs and potential side effects.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://academic.oup.com/eurheartj/article/29/22/2667/496862
[3] https://link.springer.com/article/10.1007/s40256-014-0081-2