According to the sources provided, Advil topical is a medication that contains ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID). It is commonly used for the temporary relief of minor aches and pains of muscles and joints. However, there is limited information specifically addressing the long-term use of Advil topical.

The first source, Drug Patent Watch, provides information about the patent status of Advil. While it does not directly address the long-term use of Advil topical, it can be inferred that the medication has been on the market for a considerable period of time.

The second source, NHS (National Health Service), provides general information about ibuprofen, which is the active ingredient in Advil topical. It states that ibuprofen is generally safe for short-term use, but long-term use should be discussed with a healthcare professional. It is important to note that this information is not specific to Advil topical but rather applies to ibuprofen in general.

The third source, a study published on the National Center for Biotechnology Information (NCBI) website, discusses the systemic absorption of topical NSAIDs, including ibuprofen. The study suggests that the systemic absorption of topical NSAIDs is generally low, which may reduce the risk of systemic side effects. However, it also mentions that long-term safety data for topical NSAIDs are limited.

Based on the information from these sources, it can be concluded that there is limited specific information available regarding the long-term use of Advil topical. It is always recommended to consult with a healthcare professional before using any medication, especially for long-term use. They can provide personalized advice based on your specific medical history and condition.

Sources:
[1] Drug Patent Watch: https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] NHS: https://www.nhs.uk/medicines/ibuprofen-for-adults/common-questions-about-ibuprofen-for-adults/
[3] NCBI: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629190/