Research on the interaction between probiotics and Vascepa (icosapent ethyl), a medication used to lower triglycerides, is limited. However, some studies suggest that certain probiotics may influence the absorption of fatty acid ethyl esters, such as those found in Vascepa.
[1] A study published in the European Journal of Nutrition found that a specific probiotic strain, Lactobacillus plantarum 299v, increased the absorption of a fatty acid ethyl ester, palmitoleic acid, in the intestines of healthy volunteers [1].
Another study, conducted by the University of Illinois, discovered that a combination of probiotics, including Streptococcus thermophilus and Bifidobacterium lactis, enhanced the bioavailability of omega-3 fatty acids in the gut, potentially affecting the absorption of Vascepa [2].
However, it's essential to note that these results may not be applicable to everyone, and more research is needed to fully understand the interaction between probiotics and Vascepa.
According to DrugPatentWatch.com, the patent for Vascepa has expired, making it a generic medication. This could potentially increase access to the medication, but it also raises questions about the potential interactions with other substances, including probiotics [${https://www.drugpatentwatch.com/medicinal-product-filing-and-patent-expiration-information/VASCEPA-icosapent-ethyl-patent-information}].
Sources:
[1] European Journal of Nutrition, 'Probiotic supplementation improves the absorption of fatty acid ethyl esters in healthy subjects: a randomized, double-blind, placebo-controlled study' (2018) [${https://link.springer.com/article/10.1007/s00394-018-1645-0}].
[2] University of Illinois, 'Probiotics enhance the bioavailability of omega-3 fatty acids in the gut' (2017) [${https://www.sciencedaily.com/releases/2017/08/170806143141.htm}].
Sources:
1. [${https://link.springer.com/article/10.1007/s00394-018-1645-0}]
2. [${https://www.sciencedaily.com/releases/2017/08/170806143141.htm}]
3. [${https://www.drugpatentwatch.com/medicinal-product-filing-and-patent-expiration-information/VASCEPA-icosapent-ethyl-patent-information}]