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Glycerol monocaprylocaprate?

See the DrugPatentWatch profile for Glycerol

What is glycerol monocaprylocaprate (GML)?

Glycerol monocaprylocaprate (often shortened to GML) is a lipid ingredient used in foods and some personal-care and medical applications. Chemically, it is a glycerol ester of caprylic acid and capric acid (the “monocaprylocaprate” part refers to those fatty-acid components). [1]

What is glycerol monocaprylocaprate used for?

GML is commonly used as a functional lipid ingredient, including as an emulsifier or carrier-type ingredient in formulations where fat-based components need to be dispersed or stabilized. It can also be used in products where antimicrobial activity is desired, since fatty-acid derivatives are often explored for that purpose. [1]

Is glycerol monocaprylocaprate safe?

Safety depends on the product category (food vs. skin-contact product vs. medicinal use) and the specific regulatory framework that applies. Safety assessments for ingredients like GML typically consider absorption, metabolism, and toxicology data at relevant exposure levels. [1] If you are asking for a specific product, the safest way to confirm is to check the ingredient’s regulatory status and the maximum allowed use level in that region.

How is glycerol monocaprylocaprate different from related compounds?

GML sits in a family of mono- and diglycerides and fatty-acid esters. Changing the fatty-acid chain lengths or the degree of esterification (mono- vs. di-) changes physical properties like solubility, emulsifying behavior, and how the compound interacts with microbes or skin. Those differences can affect how it performs in a formulation. [1]

How is glycerol monocaprylocaprate typically listed on labels?

It may appear under the name “glycerol monocaprylocaprate” or as an abbreviation like “GML,” depending on the labeling rules in the country and the product type. Checking the exact ingredient name on the label is the fastest way to confirm that the product is using GML (not a similar fatty-acid ester). [1]

Sources

  1. https://pubchem.ncbi.nlm.nih.gov/compound/Glycerol-monocaprylocaprate


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