Standard Administration Method
Darolutamide (Nubeqa) is taken orally as film-coated tablets, twice daily, with or without food.[1] The recommended dose is 600 mg (two 300 mg tablets) every 12 hours.[1]
Dosage for Specific Conditions
For non-metastatic castration-resistant prostate cancer (nmCRPC), it's 600 mg twice daily alongside continued androgen deprivation therapy.[1] No dose adjustments are needed for mild to moderate liver or kidney impairment, but it's not recommended for severe cases.[1]
How to Take It
Swallow tablets whole; do not chew, crush, or split them.[1] Consistent timing helps maintain steady drug levels. If a dose is missed, take it as soon as remembered unless it's near the next dose—then skip and resume normally.[1]
What Happens If You Miss Doses or Stop
Missing doses may reduce effectiveness against cancer progression. Stopping abruptly isn't advised without doctor guidance, as it could affect treatment outcomes.[1]
Common Patient Questions on Use
Patients often ask about food interactions—none significant, so no restrictions.[1] Tablets contain lactose, relevant for lactose-intolerant individuals.[1] Store at room temperature, away from moisture.[1]
[1]: FDA Label for Nubeqa (darolutamide)