Methylprednisolone patent?

Short answer: The core methylprednisolone molecule is no longer protected by a basic patent in most major markets and is available as a generic. However, there have historically been (and in some cases may still be) patents on specific salts and injectable formulations (for example methylprednisolone sodium succinate and methylprednisolone acetate), as well as on certain manufacturing processes or specific use claims. Patents are highly jurisdiction- and date-specific, so current status can vary by country and by the exact salt/ formulation.

How to check current status (recommended):
- Use patent databases and search for both the molecule and its common salt/formulations:
- Google Patents (search terms like “methylprednisolone”, “methylprednisolone sodium succinate”, “methylprednisolone acetate”)
- USPTO PatFT (US patents)
- Espacenet (European/EPO)
- WIPO Patentscope (PCT)
- Helpful search queries:
- methylprednisolone patent
- methylprednisolone sodium succinate patent
- methylprednisolone acetate patent
- Depo-Medrol patent (formulation)
- Solu-Medrol patent (injectable sodium succinate formulation)

If you tell me the country or region and whether you’re interested in the core molecule, a specific salt (e.g., sodium succinate, acetate), or a particular formulation, I can do a targeted check and summarize the current patent status for you.