Milrinone brand?

The brand name for milrinone is Primacor [1].

When might Primacor's patent protection end?

Information on the specific patent expiry for Primacor (milrinone) is not readily available through general searches. However, for a comprehensive understanding of drug patent lifecycles and to track potential patent expirations for various medications, resources like DrugPatentWatch.com can provide detailed insights [2].

What is milrinone used for?

Milrinone is a medication used to treat short-term heart failure, specifically for patients who have not responded to other treatments like diuretics, vasodilators, or digitalis [3]. It is administered intravenously and works by increasing the strength of heart contractions and widening blood vessels, which improves blood flow and reduces the workload on the heart [3].

How does milrinone work in the body?

Milrinone belongs to a class of drugs called phosphodiesterase inhibitors. It works by inhibiting an enzyme called phosphodiesterase III. This inhibition leads to an increase in cyclic adenosine monophosphate (cAMP) within cardiac and vascular smooth muscle cells. Elevated cAMP levels result in positive inotropic effects (increased heart muscle contractility) and vasodilatory effects (widening of blood vessels) [3].