See the DrugPatentWatch profile for Captopril
Captopril is an angiotensin-converting enzyme (ACE) inhibitor. Its active pharmaceutical ingredient is captopril. The drug also contains inactive ingredients that aid in its formulation and delivery. These inactive ingredients can vary by manufacturer but typically include binders, fillers, disintegrants, and lubricants [1].
What other medications work like Captopril?
Captopril belongs to a class of drugs called ACE inhibitors. Other ACE inhibitors include enalapril, lisinopril, ramipril, and benazepril. These medications work by blocking the action of angiotensin-converting enzyme, which helps to relax blood vessels, thereby lowering blood pressure [2].
When does the patent for Captopril expire?
Captopril, originally developed by Squibb (now Bristol Myers Squibb), has long been off-patent. The initial patents for captopril expired many years ago, allowing for the production of generic versions of the drug [3].
What is Captopril used to treat?
Captopril is prescribed to treat high blood pressure (hypertension) and heart failure. It can also be used to improve survival after a heart attack [1].
What are the potential side effects of Captopril?
Common side effects of captopril include dizziness, fatigue, rash, and a persistent dry cough. More serious side effects, though less common, can include kidney problems, a severe allergic reaction, and a drop in white blood cell count [1].