Ibuprofen is a commonly used painkiller and anti-inflammatory drug that is available over-the-counter (OTC) and through prescription. It is generally safe to take ibuprofen with other medications, but there are some exceptions that should be noted.

According to the NHS [2], ibuprofen can interact with some medications and herbal supplements, which can increase the risk of side effects or reduce the effectiveness of the drugs. Some of the medications that may interact with ibuprofen include blood thinners, steroids, antidepressants, and diuretics. Additionally, taking ibuprofen with other painkillers such as aspirin or acetaminophen can increase the risk of side effects and should be avoided unless advised by a doctor.

Drug Patent Watch [1] lists several drugs that may interact with ibuprofen, including lithium, methotrexate, and certain blood pressure medications. It is important to consult with a healthcare provider before taking ibuprofen if you are currently taking any prescription medications or have any underlying medical conditions.

GoodRx [3] also provides a list of medications that may interact with ibuprofen, along with potential side effects and precautions. For example, taking ibuprofen with certain antibiotics can increase the risk of stomach bleeding, while taking it with certain heart medications can increase the risk of heart attack or stroke.

In conclusion, while ibuprofen is generally safe to take with other medications, it is important to be aware of potential interactions and to consult with a healthcare provider before taking ibuprofen if you are currently taking any prescription medications or have any underlying medical conditions.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/IBUPROFEN
[2] https://www.nhs.uk/medicines/ibuprofen-for-adults/taking-ibuprofen-with-other-medicines-and-herbal-supplements/
[3] https://www.goodrx.com/ibuprofen/interactions