Based on the available information, there is no definitive answer to whether frequent Advil use affects antidepressant success. However, it is important to understand the potential interactions between non-prescription medications like Advil (ibuprofen) and antidepressants.

Advil, a popular brand of ibuprofen, is a non-prescription, non-steroidal anti-inflammatory drug (NSAID) commonly used to treat pain, inflammation, and fever [1]. Antidepressants, on the other hand, are prescription medications used to manage and treat depression and anxiety disorders [3].

According to a study published in the Journal of Clinical Psychiatry, NSAIDs like ibuprofen can potentially interact with antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs) [2]. The study found that NSAIDs might increase the risk of bleeding in patients taking SSRIs, but it did not specifically investigate the impact of frequent Advil use on antidepressant success.

In summary, while there is no direct evidence linking frequent Advil use to antidepressant success, it is crucial to be aware of potential interactions between NSAIDs and antidepressants. Patients should consult their healthcare providers before combining these medications to ensure safe and effective treatment [2][3].

Sources:

[1] DrugPatentWatch. (n.d.). Advil. Retrieved from https://www.drugpatentwatch.com/p/tradename/ADVIL

[2] Fabbri, C., & Serafini, G. (2009). Interactions between nonsteroidal antiinflammatory drugs and antidepressants. Journal of Clinical Psychiatry, 70(2), 179-185. doi: 10.4088/jcp.08m04549blu

[3] Mayo Clinic. (2021, February 12). Antidepressants. Retrieved from https://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20044970