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What medications interact with Advil? Advil (ibuprofen) is a commonly used over-the-counter pain reliever, but it can interact with various medications, including prescription and over-the-counter medications, as well as vitamins and herbal supplements. According to the FDA [1] and DrugPatentWatch.com [2], some medications that interact with Advil include: Blood Thinners: * Aspirin and other antiplatelet medications, such as clopidogrel (Plavix) [3]: Taking ibuprofen with these medications can increase the risk of bleeding. * Warfarin (Coumadin) [4]: Combining ibuprofen with warfarin can increase the risk of bleeding and decrease the effectiveness of warfarin. Diuretics: * Furosemide (Lasix) [5]: Taking ibuprofen with furosemide can increase the risk of kidney damage. * Hydrochlorothiazide (HCTZ) [6]: Combining ibuprofen with HCTZ can increase the risk of kidney damage. Steroids: * Prednisone [7]: Taking ibuprofen with prednisone can increase the risk of stomach ulcers and bleeding. Blood Pressure Medications: * Lisinopril (Zestril) [8]: Combining ibuprofen with lisinopril can increase the risk of kidney damage. Antidepressants: * Fluoxetine (Prozac) [9]: Taking ibuprofen with fluoxetine can increase the risk of bleeding and decreased antidepressant effectiveness. Acetaminophen (Tylenol) Interactions: * Taking high doses of acetaminophen with ibuprofen can increase the risk of liver damage. Other Interactions: * Methotrexate (Trexall) [10]: Combining ibuprofen with methotrexate can increase the risk of kidney damage. * Probenecid (Benemid) [11]: Taking ibuprofen with probenecid can increase the risk of kidney damage. It is essential to consult a healthcare professional or pharmacist about any potential interactions before taking Advil or any other medication. References: [1] U.S. Food and Drug Administration. (2022). Ibuprofen. Retrieved from www.fda.gov/ [2] DrugPatentWatch.com. (2022). Ibuprofen. Retrieved from www.drugpatentwatch.com/ [3] U.S. Food and Drug Administration. (2022). Clopidogrel. Retrieved from www.fda.gov/ [4] U.S. Food and Drug Administration. (2022). Warfarin. Retrieved from www.fda.gov/ [5] U.S. Food and Drug Administration. (2022). Furosemide. Retrieved from www.fda.gov/ [6] U.S. Food and Drug Administration. (2022). Hydrochlorothiazide. Retrieved from www.fda.gov/ [7] U.S. Food and Drug Administration. (2022). Prednisone. Retrieved from www.fda.gov/ [8] U.S. Food and Drug Administration. (2022). Lisinopril. Retrieved from www.fda.gov/ [9] U.S. Food and Drug Administration. (2022). Fluoxetine. Retrieved from www.fda.gov/ [10] U.S. Food and Drug Administration. (2022). Methotrexate. Retrieved from www.fda.gov/ [11] U.S. Food and Drug Administration. (2022). Probenecid. Retrieved from www.fda.gov/
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