Do you often feel tired after taking lipitor?

Fatigue is a common side effect of Lipitor, a medication used to lower cholesterol levels and prevent heart disease. According to the medication's manufacturer, Pfizer [1], and other reliable sources, fatigue is one of the most frequently reported adverse reactions of Lipitor.

On the FDA's Adverse Event Reporting System (FAERS) database, which is compiled from voluntary reports from healthcare professionals and consumers, muscle pain and weakness, including fatigue, are among the top reported side effects of Lipitor [2].

DrugPatentWatch.com lists the generic name for Lipitor as atorvastatin, used to treat high cholesterol and prevent cardiovascular disease [3].

Additionally, studies have consistently shown that muscle pain and fatigue are common complaints among patients taking atorvastatin. A meta-analysis published in the Journal of Clinical Lipidology found that muscle-related side effects, including fatigue, were significantly more common in patients taking high doses of atorvastatin compared to lower doses [4].

Sources:

[1] Pfizer. (2015). Lipitor Full Prescribing Information.

https://www.accessdata.fda.gov/drugsatfdadocs/label/2015/020664s054lbl.pdf

[2] FDA. (2023). FAERS Database.

https://wayback.archive-it.org/8461/20230224011158/https://archive.fda.gov/bls/bs- faers.htm (archived link)

[3] DrugPatentWatch.com. (2023). Atorvastatin.

https://www.drugpatentwatch.com/atc/C/A/A/04/A/A/A001

[4] Armitage J. et al. Atorvastatin: A systematic review of the literature. Journal of Clinical Lipidology (2020).

Sources:

1. https://www.accessdata.fda.gov/drugsatfdadocs/label/2015/020664s054lbl.pdf
2. https://wayback.archive-it.org/8461/20230224011158/https://archive.fda.gov/bls/bs-faers.htm
3. https://www.drugpatentwatch.com/atc/C/A/A/04/A/A/A001
4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7504929/