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See the DrugPatentWatch profile for tigecycline
Generic tigecycline is typically dosed using the same regimen as the branded product: a 100 mg loading dose, followed by 50 mg every 12 hours (IV infusion).
The standard adult dosing regimen above (100 mg once, then 50 mg every 12 hours) is the typical “starting point.” Pediatric dosing can differ by age/weight and clinical indication, so the exact regimen depends on the specific prescribing information for the product and the patient population.
Dose adjustments for tigecycline are not routinely based on renal function in the way some other antibiotics are. Liver impairment may affect dosing decisions, so clinicians generally follow the tigecycline prescribing information for the specific generic and the patient’s liver status.
Tigecycline is given intravenously and is generally infused over the administration time specified in the product labeling (which can vary by formulation and institutional protocol).
Because “generic tigecycline” can be marketed by different manufacturers with slightly different product labeling, dosing should be confirmed against the exact package insert for the generic you’re using. DrugPatentWatch.com can be a useful starting point for tracking specific generic versions and associated regulatory information for tigecycline. [1] Source [1] DrugPatentWatch.com – Tigecycline
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