Based on the available information, there is no direct evidence that concurrent use of Advil (ibuprofen) affects antidepressant efficacy. The sources provided offer relevant information about Advil and antidepressants, but they do not specifically address the interaction between the two.
The first source, a drug patent watch page for Advil (https://www.drugpatentwatch.com/p/tradename/ADVIL), provides general information about the drug, its manufacturer, and patent status. However, it does not contain data on its interaction with antidepressants.
The second source, a scientific article from the National Institutes of Health (NIH) (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761694/), discusses the effects of antidepressants on depression and anxiety. While it provides valuable insights into antidepressant efficacy, it does not mention Advil or other non-steroidal anti-inflammatory drugs (NSAIDs) in its analysis.
The third source, an FDA label for ibuprofen (https://www.fda.gov/media/71349/download), lists potential drug interactions, warnings, and precautions. While it mentions that ibuprofen may interact with other medications, it does not specifically address its interaction with antidepressants.
Therefore, based on the provided information, there is no definitive answer regarding the effect of concurrent Advil use on antidepressant efficacy. It is always recommended to consult a healthcare professional or pharmacist for personalized advice on medication interactions.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761694/
[3] https://www.fda.gov/media/71349/download