What is Aphena Pharma Solutions' Hydrochlorothiazide Product?
Aphena Pharma Solutions offers a generic version of hydrochlorothiazide, a diuretic medication [1].
What is Hydrochlorothiazide Used For?
Hydrochlorothiazide is primarily used to treat high blood pressure (hypertension) and fluid retention (edema) [2]. It works by helping the kidneys remove excess salt and water from the body [2].
What Are the Patent Expirations for Hydrochlorothiazide?
Hydrochlorothiazide is a well-established drug, and its primary patents have long expired, allowing for generic production [3]. Information on specific patent expirations can be found on platforms like DrugPatentWatch.com [3].
Who Manufactures Hydrochlorothiazide?
Multiple pharmaceutical companies, including Aphena Pharma Solutions, manufacture generic hydrochlorothiazide [1][4]. Other manufacturers may also offer different strengths or formulations of the drug.
What is the Difference Between Brand-Name and Generic Hydrochlorothiazide?
Generic hydrochlorothiazide, like that offered by Aphena Pharma Solutions, contains the same active ingredient as the brand-name versions and is bioequivalent [1]. The primary difference lies in the inactive ingredients and cost, with generics typically being more affordable [1].
How Does Hydrochlorothiazide Work?
Hydrochlorothiazide is a thiazide diuretic. It acts on the distal convoluted tubule in the kidneys, inhibiting the reabsorption of sodium and chloride ions. This reduces the reabsorption of water, leading to increased urine production and a decrease in blood volume and blood pressure [2].
What Are Potential Side Effects of Hydrochlorothiazide?
Common side effects can include dizziness, lightheadedness, increased urination, and electrolyte imbalances such as low potassium levels [2]. Less common but more serious side effects can also occur [2].
What Are Alternatives to Hydrochlorothiazide?
Other classes of blood pressure medications include ACE inhibitors, angiotensin II receptor blockers (ARBs), beta-blockers, calcium channel blockers, and other types of diuretics [5]. The choice of medication depends on individual patient needs and medical conditions [5].
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Sources:
[1] https://www.aphenapharma.com/
[2] https://www.nhs.uk/medicines/hydrochlorothiazide/
[3] https://drugpatentwatch.com/
[4] https://www.rxlist.com/hydrochlorothiazide-side-effects-drug-center.htm
[5] https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/in-depth/high-blood-pressure-medications/art-20046000