Does lupron treat prostate cancer?

Does Lupron treat prostate cancer?

Lupron is approved to treat advanced prostate cancer. It works by lowering testosterone levels, which slows the growth of hormone-sensitive tumors.

How does Lupron work for prostate cancer?

Lupron is a GnRH agonist. It initially causes a temporary surge in testosterone, followed by long-term suppression. This medical castration reduces androgen-driven tumor growth.

When does Lupron start working?

The testosterone surge lasts about 7 to 14 days. Full suppression usually occurs by week 4. Patients receive injections every 1, 3, 4, or 6 months depending on the formulation.

Can Lupron be used alone?

Lupron can be used alone for advanced prostate cancer. It is also combined with anti-androgens such as bicalutamide to block the initial testosterone flare.

What side effects do patients report?

Common concerns include hot flashes, fatigue, bone loss, and sexual dysfunction. Some patients worry about cardiovascular risks and cognitive effects with long-term use.

When does the Lupron patent expire?

The original compound patents expired decades ago. Generic leuprolide acetate versions are widely available.