Alcohol can indeed interfere with the effectiveness of antibiotics. When alcohol and antibiotics are consumed together, it can lead to various adverse effects. According to Drug Patent Watch [1], alcohol can potentially reduce the effectiveness of certain antibiotics, making the treatment less efficient. The Mayo Clinic [2] also highlights that alcohol can interact with antibiotics, causing side effects like nausea, vomiting, headache, rapid heart rate, and liver damage. The National Center for Biotechnology Information [3] emphasizes that the combination of alcohol and antibiotics can impact the body's ability to metabolize the medication properly, potentially reducing its efficacy. Therefore, it is generally advised to avoid consuming alcohol while taking antibiotics to ensure the treatment's optimal effectiveness.

Sources:
[1] drugpatentwatch.com
[2] mayoclinic.org
[3] ncbi.nlm.nih.gov